The profit of mobile phone sales in JD.com's self-operated mobile phone store varies depending on factors such as brands, models, and market demand, so it is impossible to determine a unified answer. Different brands and models have different prices and cost factors, so the sales profit will also be different. In addition, JD.com's self-operated stores may also adjust the price and profit margin of products according to different marketing strategies and sales volumes.

Generally speaking, in order to ensure normal operations, the retail industry usually has a certain profit margin on the basis of its cost price. The specific profit margin depends on many factors such as the brand, model, and market demand of the product. Generally speaking, the profit margin may fluctuate between a few percentage points and dozens of percentage points.

It should be noted that the profit of an enterprise is a multi-dimensional indicator, which is not only affected by the purchase cost, but also by many factors such as operating costs, marketing expenses, market demand, and competitive pressure. Furthermore, the sales profit of JD.com's self-operated mobile phone store, in addition to affecting the purchase price of brand manufacturers and agents, is also affected by many factors such as the handling fee, delivery cost, and after-sales processing of the JD platform itself. Therefore, sales profits of different channels and companies may vary greatly, and the specific figures cannot be determined.