Of course you can. You can still open a store after self-registering on Amazon. As an e-commerce platform, Amazon welcomes merchants to join. As long as you meet Amazon's entry standards, you can open a store whether you self-register or through investment. However, self-registered stores need to submit more materials and information during the entry process to prove that they meet Amazon's entry standards.

In addition, self-registered stores need to strictly abide by Amazon's seller regulations during operation, otherwise they may face corresponding penalties.