秘鲁、厄瓜多尔、哥伦比亚、委内瑞拉、圭亚那、苏里南、玻利维亚和巴西等国亚马逊河流域北起巴西布朗库,玻利维亚南部的马代拉(Madeira)河河源(南纬约20°),西起厄瓜多尔昆卡(Cuenca)的保特(Paute)河河源(西经79°31′),东至巴西的马拉若湾(西经约48°),整个流域跨纬度25°、经度31°30′,流域面积达691.5万km2,约占整个南美洲面积的39%,其中干流穿越的亚马孙平原面积达560万km2,是世界上最大的平原。
The Amazon River basin in Peru, Ecuador, Colombia, Venezuela, Guyana, Suriname, Bolivia and Brazil starts from the source of the Madeira River in southern Bolivia (about 20° south latitude) in the north of Brazil's Branco, and the source of the Paute River in Cuenca, Ecuador (79°31′ west longitude) in the west, and ends at the Marajo Bay in Brazil (about 48° west longitude) in the east. The entire basin spans 25° latitude and 31°30′ longitude, with a drainage area of 6.915 million km2, accounting for about 39% of the entire area of South America. The Amazon Plain, which the main stream passes through, covers an area of 5.6 million km2, the largest plain in the world.