Sino-Singapore Knowledge City is a section located in Huangpu District.

Sino-Singapore Guangzhou Knowledge City is the vision of the region after Suzhou Industrial Park and Tianjin Eco-City. It is to use knowledge economy as an innovation model, gather high-end industries and talents, and build a city with highly harmonious and sustainable economic, cultural and ecological development. The area will accommodate 540,000 people in the future. Currently, there is a branch line of Metro Line 14 in the area, which can connect to the main line of Metro Line 14 to reach Baiyun and Conghua, and connect to Line 21 to reach Zengcheng and Tianhe. In addition, the Guangzhou-Dongguan-Shenzhen intercity rail connects the Central Knowledge City with the surrounding cities of Guangzhou. At present, the area has introduced large enterprises such as JD.com, Alibaba, and Didi, as well as many hospitals such as the Nanfang Hospital General Hospital and the Affiliated Cancer Hospital of Sun Yat-sen University. In terms of education, there are also schools such as Guangzhou No. 2 Middle School and Guangzhou Experimental Middle School. The future development trend is also good.